Robert A. Smith, PhD, is a cancer epidemiologist and senior vice president of Early Cancer Detection Science for the American Cancer Society (ACS). For most of his tenure at the ACS, he has led the development of cancer screening guidelines and been active in research on the effectiveness of cancer screening, utilization of cancer screening, improving the quality of cancer screening, and new cancer screening technology. In addition to leading cancer screening guideline development, Smith is co-chair of the ACS National Colorectal Cancer Roundtable, and principal investigator of the ACS National Lung Cancer Roundtable. He has served and continues to serve on many US and international research and health policy advisory committees. He has been a member of the Prevention Committees for three International Agency for Research on Cancer (IARC) Screening Handbooks (Breast, Colorectal, and Cervix), and presently serves on the Steering Committee of the International Cancer Screening Network.